Bioinformatics

partial_insulin_sequence_logo

Insulin family sequence logo, showing the relative likelihood of different amino acids at different places in the sequence. The sequence logo was constructed using partial sequences from human, rabbit, horse, sheep, pig, chicken, alligator, and cod insulin proteins.

BMTH 312 Bioinformatics

Course Topics

  • Central Dogma of Biology
  • Sequence Bioinformatics:
    • protein sequence databases
    • pairwise alignment
    • multiple sequence alignment
    • protein sequence families
  • Structural Bioinformatics
    • protein structure databases
    • protein structure alignment
    • protein structure families
  • Applications:
    • Insulin and Metabolic Diseases
    • Malaria Transmission
    • Breast Cancer and the Estrogen Receptor

Textbook

Introduction to Computational Proteomics by Golan Yona

Software

1mso_human_insulin

Structure of the human insulin monomer protein.

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About Yosi Shibberu

Professor of Mathematics, Rose-Hulman Institute of Technology, Terre Haute, Indiana 47803, USA
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